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Complete the following questionnaire for - IC2019_Summer Postdoctoral Fellowship in CFD - Multiscale fluid dynamics modelling of cellular transport and adhesion using particle methods  (239 KB)

Topic: Multiscale fluid dynamics modelling of cellular transport and adhesion using particle methods

Applications are invited for a postdoctoral position in computational biomicrofluidics at the CFD group (BCAM). The focus of the project will be on multiscale modelling of the dynamics and adhesion of cells using Smoothed Particle Hydrodynamics and Dissipative Particle Dynamics methods.

In many biological processes it is important to predict accurately the cellular transport, separation and deposition close to walls in presence of a complex unsteady flow. This is critical to control drug delivery and/or cellular sorting under microfludics conditions, but also for the understanding of several cardiovascular pathologies such as, for example, atherosclerosis. This is a degenerative disease of the arterial wall that is thought to be initiated due to inflammation of the arterial endothelium, promoting the over-deposition of white blood cells. This anomalous WBC accumulation is site-specific and can lead to initial stage lesions or, on a long-term timescale, atherosclerotic plaques. To study these complex flow problems, we have recently developed a multiscale transport model for leukocytes and coupled it to an endothelial cell receptor binding model in order to link the flow transport and surface biology.

The postdoctoral candidate will work under the supervision of Prof. Marco Ellero (CFD group, BCAM) on the developments and use of novel mesoscopic particle-simulation methods to better understand the dynamics and adhesion of cells under microfluidics conditions. This task will be performed in collaboration with Prof. Jesus Ruiz-Cabello (CIC Biomagune) and the eHealth and Biomedical Department of VICOMTECH, an applied research centre in the Basque Country working on innovative technological solutions in the biomedical sector.

Deadline: August 20th 2019, 14:00 CET. (UTC+1) .

Applications will be evaluated in a continuous manner, with a response period no longer than 4 weeks after the call deadline .

((required)) Compulsory field.

Call is CLOSED

Eusko Jaurlaritza - Gobierno Vasco ikerbasque - Basque Foundation for Science Bizkaia xede. Bizkaiko Foru Aldundia innobasque - Agencia vasca de la innovación Universidad del PaÌs Vasco (UPV/EHU)