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Modeling impairment of ionic regulation with extended Adaptive Exponential integrate-and-fire models

Depannemaecker, D.; Tesler, F.; Desroches, M.; Jirsa, V.; Destexhe, A. (2025-03-01)

To model the dynamics of neuron membrane excitability many models can be considered, from the most biophysically detailed to the highest level of phenomenological description. Recent works at the single neuron level have sho...

Charge Transport at Atomic Scales in 1D-Semiconductors: A Quantum Statistical Model Allowing Rigorous Numerical Studies

Braddell, R.; Uria-Albizuri, J.; Bru, J.-B.; Rodrigues, S. (2025-06-05)

There has been a recent surge of interest in understanding charge transport at atomic scales. The motivations are myriad, including understanding the conductance properties of peptides measured experimentally. In this study,...

Biphasic changes in hippocampal granule cells after traumatic brain injury

Danielewicz, J.; Llamosas, N.; Durá, I.; Barros de Souza, D.; Rodrigues, S.; Encinas, J.M.; Mateos, D.M. (2025-08-01)

Traumatic brain injury (TBI) leads to a wide range of long-lasting physical and cognitive impairments. Changes in neuronal excitability and synaptic functions in the hippocampus have been proposed to underlie cognitive alter...

Discontinuity-Induced Dynamics in the Conductance-Based Adaptive Exponential Integrate-and-Fire Model

Desroches, M.; Kowalczyk, P.; Rodrigues, S. (2025-01-01)

In this article, we present a computational study of the Conductance-Based Adaptive Exponential (CAdEx) integrate-and-fire neuronal model, focusing on its multiple timescale nature, and on how it shapes its main dynamical re...